Natural Biopolymers for Bone Tissue Engineering: A Brief Review

•The review emphasizes the critical characteristics such as structure, degradability, and, the biocompatibility of natural biopolymers for bone tissue engineering.•The document embraces the information about various fabrication technique to achieve the desired pores size and mechanical strength of the scaffolds.•Further, the review comprises the latest advances in biopolymer modification intended for improved characteristics for bone tissue engineering. Tissue engineering is a well-proven technique for the creation of functional alternatives for regenerative medicine and plays a critical role in patient treatment. Several natural-origin biopolymers such as chitosan, hyaluronic acid, gelatin, collagen, etc. are extensively explored for various biomedical applications. Among, these polymers are exclusively investigated in tissue engineering applications due to their highly favorable properties, such as high biocompatibility, slow degradation, mechanical tenability, structural similarity with native tissues, bioactivity, etc. The present review summarizes the recent advances of biopolymers in bone tissue engineering It also covers the topic of natural polymer modification to achieve superior characteristics primarily mechanical properties towards bone regeneration and discussed the best methods for dealing with them. Therefore, the review can drive the development of biomimetic materials for futuristic applications. [Display omitted]