Efficacy of walnut supplementation in managing overweight and obesity: A meta-analysis of randomized clinical trials

[Display omitted] •There was no significant weight loss with walnut supplementation.•There was no significant BMI reduction with walnut supplementation.•Favorable effects observed on the triglyceride concentrations.•Walnut supplementation significantly lowers total cholesterol and LDL cholesterol. This study aimed to assess how effective walnut supplementation is in managing overweight and obesity. A thorough search of PubMed, Embase, and Cochrane Central Register of Controlled Trials was carried out until March 2024. Two reviewers independently examined the suitability of studies and assessed the quality of reporting in the randomized controlled trials (RCTs) that were included. The results indicated that adding walnuts to the diet significantly lowered total cholesterol (TC) levels (p 0.05) between those who received walnut supplementation and the control groups. Based on the RCT data, it appears that walnut supplementation can effectively decrease TC and LDL-C levels. Additionally, it seems to be a safe choice for individuals who are overweight or obese, as it did not have an adverse effect on body weight.