SHBG and total testosterone levels in men with adult onset hypogonadism: what are we overlooking?

SHBG and total testosterone levels in men with adult onset hypogonadism: what are we overlooking?

Adult onset male hypogonadism (AOH) is a common clinical condition whose diagnosis and management are controversial, and is often characterized by a low level of SHBG, but our understanding of why testosterone levels are low when SHBG is low is incomplete. This retrospective chart review was perform...

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Veröffentlicht in:Clinical diabetes and endocrinology 2020-09, Vol.6 (1), p.17-17, Article 17
1. Verfasser: Winters, Stephen J
Format: Artikel
Sprache:eng
Schlagworte:
Adults
Binding sites
Care and treatment
Diabetes
Gonadotropins
Hyperthyroidism
Hypogonadism
Hypothalamus
Male hypogonadism
Metabolic syndrome
SHBG
Testosterone
Thyroid gland
Type 2 diabetes
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Zusammenfassung:Adult onset male hypogonadism (AOH) is a common clinical condition whose diagnosis and management are controversial, and is often characterized by a low level of SHBG, but our understanding of why testosterone levels are low when SHBG is low is incomplete. This retrospective chart review was performed to compare the relationship between SHBG and testosterone in the plasma of men presenting for evaluation of AOH with a cohort of men treated chronically with transdermal testosterone. The level of SHBG was 
ISSN:2055-8260
2055-8260
DOI:10.1186/s40842-020-00106-3