Public's Knowledge and Experiences Towards Pediatric Clinical Trials: Methodological Characteristics Analysis

Objective This study aims to analyze the methodological characteristics of qualitative interview studies investigating the public's knowledge and experiences regarding pediatric clinical trials and to provide reference for the design and implementation of similar research in China. Methods We conducted a comprehensive search in CNKI, WanFang Data, Vip Network, PubMed, Embase, APA PsycInfo, CINAHL, and Web of Science databases. We identified all published qualitative interview studies that explored the public's knowledge and experiences related to children's participation in clinical trials up to September 21, 2021. Eight researchers were divided into four groups, with two trained researchers in each group utilizing Note Express(v 3.2) software for pre-screening and data extraction. Literature screening, data extraction, and analysis were performed independently after consistency checks. Disagreements were resolved through team leader decisions after group discussion. The CASP Qualitative Checklist Tool was