A CT-based diagnostic nomogram and survival analysis for differentiating grade 3 pancreatic neuroendocrine tumors from pancreatic ductal adenocarcinomas

To construct a CT-based diagnostic nomogram for distinguishing grade 3 pancreatic neuroendocrine tumors (G3 PNETs) from pancreatic ductal adenocarcinomas (PDACs) and assess their respective survival outcomes. Patients diagnosed with G3 PNETs (n = 30) and PDACs (n = 78) through surgery or biopsy from...

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Veröffentlicht in:Frontiers in oncology 2024-08, Vol.14, p.1443213
Hauptverfasser: Hu, Miaomiao, Lv, Lulu, Dong, Hongfeng
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Sprache:eng
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Zusammenfassung:To construct a CT-based diagnostic nomogram for distinguishing grade 3 pancreatic neuroendocrine tumors (G3 PNETs) from pancreatic ductal adenocarcinomas (PDACs) and assess their respective survival outcomes. Patients diagnosed with G3 PNETs (n = 30) and PDACs (n = 78) through surgery or biopsy from two medical centers were retrospectively identified. Demographic and radiological information, including age, gender, tumor diameter, shape, margin, dilatation of pancreatic duct, and invasive behavior, were carefully collected. A nomogram was established after univariate and multivariate logistic regression analyses. The Kaplan-Meier survival was performed to analyze their survival outcomes. Factors with a p-value
ISSN:2234-943X
2234-943X
DOI:10.3389/fonc.2024.1443213