Relationship between sperm progressive motility and DNA integrity in fertile and infertile men

Progressive sperm motility was found to be predictive for in vitro and in vivo fertilization. There has been an increase in the literature of studies investigating whether DNA fragmentation could be associated with other semen parameters; however, few reports focused on the relationship between sperm DNA fragmentation and progressive sperm motility. We purposed here to determine the relationship between DNA fragmentation level and progressive sperm motility in different groups of infertile asthenozoospermic patients as well as in healthy men of proven fertility. Retrospective study. Andrology Laboratory of the Assisted Reproductive Technologies (ART) department of Elite fertility and gynecology center, Cairo, Egypt. Semen samples were collected and examined after liquefaction for 20 min at 37 °C from 182 patients. Patient were then classified as asthenozoospermic [(Mild asthenozoospermia; PR (progressive sperm motility) = 30–20%, n = 58), (Moderate asthenozoospermia; PR = 20–10%, n = 68) and (Severe asthenozoospermia; PR