Association and diagnostic value of a novel uric acid index to cardiovascular risk

Cardiovascular diseases (CVD) are the leading cause of death and disability worldwide. The aim of this study was to assess the association and diagnostic value of a novel uric acid index (UA index) to cardiovascular risk (CVR). and Methods: An analytical cross-sectional study was performed. We analy...

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Veröffentlicht in:Practical laboratory medicine 2021-08, Vol.26, p.e00247-e00247, Article e00247
Hauptverfasser: Rojas-Humpire, Ricardo, Jáuregui-Rodríguez, Keila, Albornoz, Silvana, Ruiz Mamani, Percy G., Gutierrez-Ajalcriña, Rosmery, Huancahuire-Vega, Salomón
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Sprache:eng
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Zusammenfassung:Cardiovascular diseases (CVD) are the leading cause of death and disability worldwide. The aim of this study was to assess the association and diagnostic value of a novel uric acid index (UA index) to cardiovascular risk (CVR). and Methods: An analytical cross-sectional study was performed. We analyzed data from the Plan for Prevention and Surveillance of Communicable and Non-Communicable Diseases at the Hospital de Huaycan, Peru. The QRISK model was used to measure the CVR. Stepwise regression models were performed to determine significant factors to predict CVR and formulate the UA index, then the association of UA index and high CVR was evaluated by Poisson regression models, and the diagnostic accuracy was verified through ROC curves. In total 291 participants (206 women and 85 men) were analyzed. The correlation between UA index to CVR was stronger (R2:0.31, p 
ISSN:2352-5517
2352-5517
DOI:10.1016/j.plabm.2021.e00247