A convenient synthesis of amino acid methyl esters

A series of amino acid methyl ester hydrochlorides were prepared in good to excellent yields by the room temperature reaction of amino acids with methanol in the presence of trimethylchlorosilane. This method is not only compatible with natural amino acids, but also with other aromatic and aliphatic...

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Veröffentlicht in:	Molecules (Basel, Switzerland) Switzerland), 2008-05, Vol.13 (5), p.1111-1119
Hauptverfasser:	Li, Jiabo, Sha, Yaowu
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino acid methyl ester hydrochlorides Amino acids Amino Acids - chemistry Chemistry Communication Esterification Esters - chemical synthesis Esters - chemistry Methanol - chemistry trimethylchlorosilane Trimethylsilyl Compounds - chemistry
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Beschreibung
Zusammenfassung:	A series of amino acid methyl ester hydrochlorides were prepared in good to excellent yields by the room temperature reaction of amino acids with methanol in the presence of trimethylchlorosilane. This method is not only compatible with natural amino acids, but also with other aromatic and aliphatic amino acids.
ISSN:	1420-3049 1420-3049
DOI:	10.3390/molecules13051111