Treatment of multiple liver metastasis from gastric carcinoma

The efficacy of operative resection of liver metastasis from colorectal cancer has been established. However, a treatment for liver metastasis from gastric cancer has not yet been established. In this study, we evaluated the efficacy of hepatic arterial infusion for synchronous hepatic metastasis fr...

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Veröffentlicht in:	World journal of surgical oncology 2007-06, Vol.5 (1), p.70-70, Article 70
Hauptverfasser:	Ojima, Hitoshi, Ootake, Sayaka, Yokobori, Takehiko, Mochida, Yasushi, Hosouchi, Yasuo, Nishida, Yasuji, Kuwano, Hiroyuki
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biopsy, Needle Cancer Care and treatment Chemotherapy Complications and side effects Dose-Response Relationship, Drug Drug Administration Schedule Female Hepatic Artery Humans Immunohistochemistry Infusion therapy Infusions, Intra-Arterial Japan Kaplan-Meier Estimate Liver cancer Liver Neoplasms - drug therapy Liver Neoplasms - mortality Liver Neoplasms - pathology Liver Neoplasms - secondary Male Middle Aged Multivariate Analysis Neoplasm Invasiveness - pathology Neoplasm Staging Palliative Care Probability Prognosis Retrospective Studies Risk Assessment Statistics, Nonparametric Stomach cancer Stomach Neoplasms - mortality Stomach Neoplasms - pathology Stomach Neoplasms - surgery Survival Analysis Treatment Outcome
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Zusammenfassung:	The efficacy of operative resection of liver metastasis from colorectal cancer has been established. However, a treatment for liver metastasis from gastric cancer has not yet been established. In this study, we evaluated the efficacy of hepatic arterial infusion for synchronous hepatic metastasis from gastric cancer. This study consisted of 37 patients [HAI group; 18 and non-HAI group; 19] with synchronous multiple liver metastases from gastric cancer at Gunma Prefecture Saiseikai-Maebashi Hospital. We retrospectively analyzed the efficacy of HAI. Response rate (CR + PR) of HAI was 83%. However, HAI treatment did not affect any improvement in the survival rate. HAI is an effective treatment for control of liver metastasis specifically. The factor effective for an improvement in the survival rate was possibly that of gastrectomy.
ISSN:	1477-7819 1477-7819
DOI:	10.1186/1477-7819-5-70