Mechanical thrombectomy of squamous cell carcinoma tumor thrombus presenting as extensive deep venous thrombosis

Background: The treatment of ilio-femoral deep venous thrombosis (DVT) has evolved with the advent of endovascular mechanical thrombectomy devices, such as the ClotTriever device (Inari, Irvine, CA). Patients may undergo percutaneous mechanical thrombectomy for thrombus removal and immediate restoration of venous drainage. Until recently, most venous thromboembolic disease has been treated with anticoagulation with or without lytic therapy. As a result of these methods, specimens have rarely been available for laboratory analysis. The ClotTriever device allows for single-session therapy without thrombolytics and specimen evaluation. Having access to these specimens may aid in elucidating the mechanisms of venous thromboembolism associated with malignancies in the future.