Reduced muscle mass as predictor of intensive care unit hospitalization in COVID-19 patients

To evaluate if reduced muscle mass, assessed with Computed Tomography (CT), is a predictor of intensive care unit (ICU) hospitalization in COVID-19 patients. In this Institution Review Board approved study, we retrospectively evaluated COVID-19 patients treated in our tertiary center from March to N...

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Veröffentlicht in:PloS one 2021-06, Vol.16 (6), p.e0253433-e0253433
Hauptverfasser: Giraudo, Chiara, Librizzi, Giovanni, Fichera, Giulia, Motta, Raffaella, Balestro, Elisabetta, Calabrese, Fiorella, Carretta, Giovanni, Cattelan, Anna Maria, Navalesi, Paolo, Pelloso, Michela, Plebani, Mario, Rea, Federico, Vettor, Roberto, Vianello, Andrea, Stramare, Roberto
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Sprache:eng
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Zusammenfassung:To evaluate if reduced muscle mass, assessed with Computed Tomography (CT), is a predictor of intensive care unit (ICU) hospitalization in COVID-19 patients. In this Institution Review Board approved study, we retrospectively evaluated COVID-19 patients treated in our tertiary center from March to November 2020 who underwent an unenhanced chest CT scan within three weeks from hospitalization.We recorded the mean Hounsfield Unit (Hu) value of the right paravertebral muscle at the level of the 12.sup.th thoracic vertebra, the hospitalization unit (ICU and COVID-19 wards), clinical symptoms, Barthel Index, and laboratory findings.Logistic regression analysis was applied to assess if muscle loss (Hu
ISSN:1932-6203
1932-6203
DOI:10.1371/journal.pone.0253433