Serum myo-inositol oxygenase levels at hospital discharge predict progression to chronic kidney disease in community-acquired acute kidney injury

Acute kidney injury (AKI) increases the risk of morbidity, mortality, and progression to chronic kidney disease (CKD). There are few data on the risk of CKD following community-acquired AKI (CA-AKI) and its predictors from developing countries. We evaluated the association of a panel of serum and ur...

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Veröffentlicht in:Scientific reports 2022-08, Vol.12 (1), p.13225-13225, Article 13225
Hauptverfasser: Kakkanattu, Tom Jose, Kaur, Jaskiran, Nagesh, Vinod, Kundu, Monica, Kamboj, Kajal, Kaur, Prabhjot, Sethi, Jasmine, Kohli, Harbir Singh, Gupta, Kishan Lal, Ghosh, Arpita, Kumar, Vivek, Yadav, Ashok Kumar, Jha, Vivekanand
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Sprache:eng
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Zusammenfassung:Acute kidney injury (AKI) increases the risk of morbidity, mortality, and progression to chronic kidney disease (CKD). There are few data on the risk of CKD following community-acquired AKI (CA-AKI) and its predictors from developing countries. We evaluated the association of a panel of serum and urine biomarkers at the time of hospital discharge with 4-month renal outcome in CA-AKI. Patients of either sex, aged between 18 and 70 years, with no underlying CKD, and with CA-AKI were recruited at the time of discharge from hospital in this prospective observational study. Levels of serum and urine biomarkers were analyzed and association between these markers and development of CKD, defined as eGFR 
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-022-17599-w