Generation of a human induced pluripotent stem cell (iPSC) line (JUCTCi011-A) from skin fibroblasts of a healthy Jordanian male subject

Human induced pluripotent stem cell line (JUCTCi011-A) was generated from skin fibroblasts obtained from a 34-year-old healthy male subject from Jordan. The generated iPSCs showed typical embryonic-like characteristics. They retained their normal karyotype similar to their parental dermal fibroblast...

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Veröffentlicht in:Stem cell research 2020-10, Vol.48, p.101923-101923, Article 101923
Hauptverfasser: Ababneh, Nidaa A., Al-Kurdi, Ban, Ali, Dema, Barham, Raghda, Sharar, Nour, Mrahleh, Mairvat M., Salah, Bareqa, Awidi, Abdalla
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Sprache:eng
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Zusammenfassung:Human induced pluripotent stem cell line (JUCTCi011-A) was generated from skin fibroblasts obtained from a 34-year-old healthy male subject from Jordan. The generated iPSCs showed typical embryonic-like characteristics. They retained their normal karyotype similar to their parental dermal fibroblast cells, expressed pluripotency markers and showed a differentiation potential into three germ layers as demonstrated by immunostaining and flow cytometry. This generated cell line can be used in disease modeling studies, to serve as a healthy control line and to help in developing novel therapeutic strategies for patients with hereditary neuromuscular diseases.
ISSN:1873-5061
1876-7753
DOI:10.1016/j.scr.2020.101923