Role of the intestinal MALT in pathogenesis of the IgA-nephropathy

Modern view on pathogenesis of immunoglobulin (Ig)A-nephropathy and possible relation to intestinal MALT-system activity is presented in the article. Aberrant glycosylation of IgA and increased association of IgA-nephropathy with intestinal diseases or abnormal intestinal permeability are discussed...

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Veröffentlicht in:	Terapevtic̆eskii arhiv 2021-06, Vol.93 (6), p.724-728
Hauptverfasser:	Guliaev, Sergei V., Strizhakov, Leonid A., Chebotareva, Natalia V., Moiseev, Sergei V.
Format:	Artikel
Sprache:	eng ; rus
Schlagworte:	immunoglobulin a immunoglobulin a-nephropathy intestinal permeability malt аberrant glycosylation of immunoglobulin a
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Beschreibung
Zusammenfassung:	Modern view on pathogenesis of immunoglobulin (Ig)A-nephropathy and possible relation to intestinal MALT-system activity is presented in the article. Aberrant glycosylation of IgA and increased association of IgA-nephropathy with intestinal diseases or abnormal intestinal permeability are discussed in details. Based on supposed entero-renal pathogenesis of the disease future treatment modalities are considered. Relevant worlds literature is cited.
ISSN:	0040-3660 2309-5342
DOI:	10.26442/00403660.2021.06.200868