Design, Synthesis and Bioactivities of Novel Isoxazole-Containing Pyrazole Oxime Derivatives

In this study, in order to find novel biologically active pyrazole oxime derivatives, twenty-eight new pyrazole oxime compounds containing a substituted isoxazole ring were synthesized and evaluated for their acaricidaland insecticidal activities. Bioassays exhibited that some target compounds indicated good acaricidal and insecticidal activities against , , , and . Especially, compounds , , , and showed 100.00%, 90.56%, 90.78%, and 90.62% insecticidal activities against at the concentration of 20 μg/mL, respectively, compounds and had 70.86% and 100.00% insecticidal activities against at 20 μg/mL, respectively.