Comparison of a Five-Year Survival and Cancer Recurrence between Laparoscopically Assisted and Open Colonic Resections due to Adenocarcinoma-a Single Centre Experience

: When resecting colon adenocarcinoma, surgeons decide between the use of laparoscopically assisted and open surgery. Laparoscopic resection is known to have short-term benefits over an open operation. However, researchers are not as unified about the long-term findings. The aim of this research is...

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Veröffentlicht in:Medicina (Kaunas, Lithuania) Lithuania), 2020-02, Vol.56 (2), p.93
Hauptverfasser: Janež, Jurij, Škapin, Armand D
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Sprache:eng
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Zusammenfassung:: When resecting colon adenocarcinoma, surgeons decide between the use of laparoscopically assisted and open surgery. Laparoscopic resection is known to have short-term benefits over an open operation. However, researchers are not as unified about the long-term findings. The aim of this research is to elaborate on five-year post-operative differences in survival and cancer recurrence between these two different approaches. : 74 enrolled patients were evaluated five years after a primary operation. We collected dates of deaths of deceased patients and time after operation of possible recurrences. Carcinoma staging was done by a pathologist after operation. Blood samples were taken before surgery in order to measure tumor markers (CA19-9 and CEA). : Survival after colonic adenocarcinoma surgery did not differ between the two different surgical approaches ( = 0.151). Recurrence of cancer was not associated with the type of operation ( = 0.532). Patients with recurrence had a 37.6 times greater hazard ratio of dying (95% CI: [12.0, 118]; < 0.001). Advanced age adversely affected survival: patients aged
ISSN:1648-9144
1010-660X
1648-9144
1010-660X
DOI:10.3390/medicina56020093