Low-Salt Intake during Mating or Gestation in Rats Is Associated with Low Birth and Survival Rates of Babies

Low-Salt Intake during Mating or Gestation in Rats Is Associated with Low Birth and Survival Rates of Babies

We investigated the influence of maternal salt restriction during mating or gestation on birth rate and offspring growth in Dahl salt-sensitive rats (DS). DS were divided into 5 groups: DS fed a low-salt (0.3% NaCl, w/w) (DS-low) or high-salt (4% NaCl, w/w) diet (DS-high) during mating and DS-high o...

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Veröffentlicht in:Journal of Nutrition and Metabolism 2014-01, Vol.2014 (2014), p.50-54
Hauptverfasser: Sakuyama, Hiroe, Shimizu, Namiko, Du, DongDong, Hara, Anna, Chou, Ranna, Uehara, Yoshio
Format: Artikel
Sprache:eng
Schlagworte:
birth rate
Health aspects
low sodium diet
metabolism
mothers
neonates
pregnancy
Pregnancy, Complications of
Pregnant women
progeny
pups
rats
Risk factors
Salt
sodium chloride
survival rate
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Zusammenfassung:We investigated the influence of maternal salt restriction during mating or gestation on birth rate and offspring growth in Dahl salt-sensitive rats (DS). DS were divided into 5 groups: DS fed a low-salt (0.3% NaCl, w/w) (DS-low) or high-salt (4% NaCl, w/w) diet (DS-high) during mating and DS-high or DS-low during gestation, and DS fed regular chow (0.75% NaCl, w/w) (DS-regular) throughout mating and gestation. During the unspecified periods, the rats were given regular chow. DS-low during mating delivered fewer infants than high-salt mothers (P
ISSN:2090-0724
2090-0732
2090-0732
DOI:10.1155/2014/212089