Curcumin Ag nanoconjugates for improved therapeutic effects in cancer

Curcumin has a broad spectrum of pharmacological activities, one of them is anticancer activity that is mediated through multiple mechanisms. The major disadvantage associated with the use of curcumin is its low bioavailability due to its poor aqueous solubility. Nanoformulations of curcumin provide...

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Veröffentlicht in:	International journal of nanomedicine 2018, Vol.13 (T-NANO 2014 Abstracts), p.75-77
Hauptverfasser:	Shah, Darshini, Savaliya, Reema, Patel, Pal, Kansara, Krupa, Pandya, Alok, Dhawan, Alok, Singh, Sanjay
Format:	Artikel
Sprache:	eng
Schlagworte:	anti-cancer Antineoplastic Agents, Phytogenic - administration & dosage Antineoplastic Agents, Phytogenic - pharmacology Cell Line, Tumor Curcumin Curcumin - administration & dosage Curcumin - pharmacology Drug Screening Assays, Antitumor Humans Metal Nanoparticles - chemistry Metal Nanoparticles - therapeutic use nanoconjugate Nanoconjugates - administration & dosage Nanoconjugates - chemistry Neoplasms - drug therapy Neoplasms - pathology Short Report silver nanoparticles Tyrosine - chemistry
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Beschreibung
Zusammenfassung:	Curcumin has a broad spectrum of pharmacological activities, one of them is anticancer activity that is mediated through multiple mechanisms. The major disadvantage associated with the use of curcumin is its low bioavailability due to its poor aqueous solubility. Nanoformulations of curcumin provide an effective solution for this problem. In this study, we have synthesized curcumin Ag nanoconjugates and evaluated their anticancer potential.
ISSN:	1178-2013 1176-9114 1178-2013
DOI:	10.2147/IJN.S124696