Progress of CD8+CD25+regulatory T cells in diseases
CD8+CD25+Treg can inhibit immune response and induce immune tolerance. This article reviews the changes and underlying mechanisms of CD8+CD25+Treg in pathogenesis of malignant tumors, autoimmune diseases and other common diseases such as asthma, allergic diseases, type 2 diabetes, and pre-eclampsia....
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Veröffentlicht in: | Ji chu yi xue yu lin chuang = Jichu yixue yu linchuang = Basic medical sciences and clinics 2022-12, Vol.42 (12), p.1939-1944 |
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Format: | Artikel |
Sprache: | chi |
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Online-Zugang: | Volltext |
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Zusammenfassung: | CD8+CD25+Treg can inhibit immune response and induce immune tolerance. This article reviews the changes and underlying mechanisms of CD8+CD25+Treg in pathogenesis of malignant tumors, autoimmune diseases and other common diseases such as asthma, allergic diseases, type 2 diabetes, and pre-eclampsia. The changes of CD8+CD25+Treg in different diseases are inconsistent, cell counting increased in malignant diseases but decreased in autoimmune diseases. Further understanding of CD8+CD25+Treg would supporte a basis for the prevention, treatment and improving prognosis of these diseases. |
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ISSN: | 1001-6325 |
DOI: | 10.16352/j.issn.1001-6325.2022.12.1939 |