Intrastromal keratoplasy with segment implantation in combination with corneal collagen cross-linking

Moroz et al evaluate the efficacy of intrastromal keratoplasy with intra-corneal ring segment implantation in combination with cornea I collagen cross-linking in the treatment of early and advanced keratoconus. Intra-corneal ring segments implantation and cross-linking are aimed to halt a keratoconus progression and have been successfully used to treat the disease of initial and far-advanced stages. The combination of both methods gives better functional results regardless of which method is performed as a first step. The choice of method to be performed as a first step of treatment depends on the central pachymetry and corneal thickness in a 5-7mm zone of ectasia. Interval between the first and the second step of treatment has to be three months or more.