Developing Novel Biointerfaces: Using Chlorhexidine Surface Attachment as a Method for Creating Anti‐Fungal Surfaces

There is an increasing focus in healthcare environments on combatting antimicrobial resistant infections. While bacterial infections are well reported, infections caused by fungi receive less attention, yet have a broad impact on society and can be deadly. Fungi are eukaryotes with considerable shar...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Global Challenges 2022-05, Vol.6 (5), p.2100138-n/a
Hauptverfasser: Bryant, Jack A., Riordan, Lily, Watson, Rowan, Nikoi, Naa Dei, Trzaska, Wioleta, Slope, Louise, Tibbatts, Callum, Alexander, Morgan R., Scurr, David J., May, Robin C., de Cogan, Felicity
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:There is an increasing focus in healthcare environments on combatting antimicrobial resistant infections. While bacterial infections are well reported, infections caused by fungi receive less attention, yet have a broad impact on society and can be deadly. Fungi are eukaryotes with considerable shared biology with humans, therefore limited technologies exist to combat fungal infections and hospital infrastructure is rarely designed for reducing microbial load. In this study, a novel antimicrobial surface (AMS) that is modified with the broad‐spectrum biocide chlorhexidine is reported. The surfaces are shown to kill the opportunistic fungal pathogens Candida albicans and Cryptococcus neoformans very rapidly (
ISSN:2056-6646
2056-6646
DOI:10.1002/gch2.202100138