Association of placental histopathological findings with COVID-19 and its predictive factors
The aims of the study are to describe the association of coronavirus disease (COVID-19) with the abnormal histopathological findings in human placenta and to highlight the potential predictors of these histopathological findings. A retrospective cohort study, held in two obstetric units from January...
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Veröffentlicht in: | Revista Brasileira de ginecologia e obstetrícia 2024-01, Vol.46 |
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Sprache: | eng |
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Zusammenfassung: | The aims of the study are to describe the association of coronavirus disease (COVID-19) with the abnormal histopathological findings in human placenta and to highlight the potential predictors of these histopathological findings.
A retrospective cohort study, held in two obstetric units from January 2021- 2022, 34 patients who were confirmed cases of COVID- 19 were followed up till the time of delivery as their placenta were sent for histopathology. Patients diagnosed with other viral infections, chorioamnionitis, or were known case of as pre-term or term pre labour rupture of membrans (PROM) were excluded as well as pre exisiting diabetes mellitus or pre-eclampsia. Data analysis were performed using STATA software version 16.
Specific histopatological findings (fetal vascular malperfusion, maternal vascular malperfusion, inflammatory pathology and thrombotic finding) were significantly high among 13 (38.2%) of the study group who got infected earlier in pregnancy (P |
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ISSN: | 0100-7203 1806-9339 1806-9339 |
DOI: | 10.61622/rbgo/2024AO03 |