Left Ventricular Diastolic Dysfunction and Progression of Chronic Kidney Disease: Analysis of KNOW-CKD Data

Background Few studies have examined the association between the early diastolic mitral inflow velocity/early diastolic mitral annulus velocity ratio (E/e') and chronic kidney disease progression. Methods and Results We reviewed data from 2238 patients with nondialysis chronic kidney disease fr...

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Veröffentlicht in:Journal of the American Heart Association 2022-07, Vol.11 (13), p.e025554
Hauptverfasser: Kang, Eunjeong, Lee, Sung Woo, Ryu, Hyunjin, Kang, Minjung, Kim, Seonmi, Park, Sue K, Jung, Ji Yong, Lee, Kyu-Beck, Han, Seung Hyeok, Ahn, Curie, Oh, Kook-Hwan
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Sprache:eng
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Zusammenfassung:Background Few studies have examined the association between the early diastolic mitral inflow velocity/early diastolic mitral annulus velocity ratio (E/e') and chronic kidney disease progression. Methods and Results We reviewed data from 2238 patients with nondialysis chronic kidney disease from the KNOW-CKD (Korean Cohort Study for Outcome in Patients With Chronic Kidney Disease); data from 163 patients were excluded because of missing content. A >50% decrease in estimated glomerular filtration rate from baseline, doubling of serum creatinine, or dialysis initiation and/or kidney transplantation were considered renal events. At baseline, median (interquartile range) ejection fraction and E/e' were 64.0% (60.0%-68.0%) and 9.1 (7.4-11.9), respectively. Proportions of ejection fraction
ISSN:2047-9980
2047-9980
DOI:10.1161/JAHA.122.025554