Synthesis of 4-aryl substituted 3,4-dihydropyrimidinones using silica-chloride under solvent free conditions

Synthesis of 4-aryl substituted 3,4-dihydropyrimidinones using silica-chloride under solvent free conditions

This paper describes an improved procedure for the efficient and facile synthesis of 4-aryl substituted 3, 4-dihydropyrimidinones under mild reaction conditions with excellent yields using inexpensive silica chloride under solvent free conditions.

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Veröffentlicht in:Molecules (Basel, Switzerland) Switzerland), 2007-07, Vol.12 (7), p.1341-1351
Hauptverfasser: Karade, Hitendra N, Sathe, Manisha, Kaushik, M P
Format: Artikel
Sprache:eng
Schlagworte:
Biginelli reaction
Chloride
Chlorides - chemistry
Dihydropyrimidinones
Pyrimidinones - chemical synthesis
Pyrimidinones - chemistry
Reagents
silica chloride
Silicon Dioxide - chemistry
solvent free
Solvents
Solvents - chemistry
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Beschreibung
Zusammenfassung:This paper describes an improved procedure for the efficient and facile synthesis of 4-aryl substituted 3, 4-dihydropyrimidinones under mild reaction conditions with excellent yields using inexpensive silica chloride under solvent free conditions.
ISSN:1420-3049
1420-3049
DOI:10.3390/12071341