Primary Cutaneous T-Cell/Histiocyte-Rich B-Cell Lymphoma: A Case Report and Literature Review

Primary Cutaneous T-Cell/Histiocyte-Rich B-Cell Lymphoma: A Case Report and Literature Review

T-cell/histiocyte-rich large B-cell lymphoma (THRLBCL) is a lymphoproliferative disorder in which the majority of cells are reactive T cells with only a minor population of neoplastic large B cells. THRLBCL is a very rare lymphoma, and most cases are nodal THRLBCL; an extranodal case of THRLBCL pres...

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Veröffentlicht in:Clinical, cosmetic and investigational dermatology cosmetic and investigational dermatology, 2023-02, Vol.16, p.309-316
Hauptverfasser: Al Harbi, Sadan Mohammed, Al Ghamdi, Nada Jomaan, Elsharkawy, Tarek Mohamed, Al Hamad, Mohammad Abdelqader, Bajawi, Sultan
Format: Artikel
Sprache:eng
Schlagworte:
B cells
Biopsy
Care and treatment
Case Report
Case reports
Cells
Hybridization
Lymphatic diseases
Lymphocytes
Lymphoma
lymphoproliferative disorder
neoplastic b cells
Non-Hodgkin's lymphomas
Radiation therapy
radiotherapy
Skin
T cells
t-cell-rich b-cell lymphoma
Tomography
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Zusammenfassung:T-cell/histiocyte-rich large B-cell lymphoma (THRLBCL) is a lymphoproliferative disorder in which the majority of cells are reactive T cells with only a minor population of neoplastic large B cells. THRLBCL is a very rare lymphoma, and most cases are nodal THRLBCL; an extranodal case of THRLBCL presenting primarily on the skin is an extremely rare occurrence with only a few cases reported in the literature. Here, we report a case of a primary cutaneous THRLBCL in a 41-year-old Saudi male who presented unusually with multiple skin lesions. He was successfully treated with electron beam radiotherapy and had a complete resolution with no recurrence as of his 24-month follow-up.
ISSN:1178-7015
1178-7015
DOI:10.2147/CCID.S395675