Gestational and perinatal outcomes in recurrent miscarriages couples treated with lymphocyte immunotherapy

This study aims to elucidate which types of recurrent miscarriage (RM) patients experienced a livebirth after paternal lymphocyte immunotherapy (LIT) and to evaluate the perinatal outcome. Retrospective analysis of a multicenter, observational study which enrolled 1096 couples with a history of two or more spontaneous miscarriages without any intercalated delivery. We conducted an intention-to-treat analysis of couples with RM treated with or without LIT regarding to gestational and perinatal outcomes. We compared groups by using the Student's -test or Kruskal-Wallis test, Fisher's exac -test and test when appropriate. The success of gestation was significantly higher in the LIT group (60.1% vs. 33.1%;