MEFV gene mutations in neuro‐Behçet's disease and neuro‐Sweet disease

MEFV gene mutations in neuro‐Behçet's disease and neuro‐Sweet disease

Mediterranean fever (MEFV) gene mutations are associated with familial Mediterranean fever (FMF). Recent studies have suggested that MEFV gene mutations may act as disease modifiers in neuro‐Behçet's (NBD) disease and neuro‐Sweet disease (NSD). We investigated MEFV genes and clinical features i...

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Veröffentlicht in:Annals of clinical and translational neurology 2019-12, Vol.6 (12), p.2595-2600
Hauptverfasser: Ishikawa, Hidehiro, Shindo, Akihiro, Ii, Yuichiro, Kishida, Dai, Niwa, Atsushi, Nishiguchi, Yamato, Matsuura, Keita, Kato, Natsuko, Mizutani, Akane, Tachibana, Kei, Hirata, Yoshinori, Matsuyama, Hirofumi, Ogawa‐Ito, Ai, Taniguchi, Akira, Tomimoto, Hidekazu
Format: Artikel
Sprache:eng
Schlagworte:
Brief Communication
Brief Communications
Fever
Laboratories
Medical imaging
Mutation
NMR
Nuclear magnetic resonance
Thrombosis
Vein & artery diseases
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Beschreibung
Zusammenfassung:Mediterranean fever (MEFV) gene mutations are associated with familial Mediterranean fever (FMF). Recent studies have suggested that MEFV gene mutations may act as disease modifiers in neuro‐Behçet's (NBD) disease and neuro‐Sweet disease (NSD). We investigated MEFV genes and clinical features in 17 patients with NBD or NSD. MEFV gene mutations were frequently observed (70.6%). Headaches and exertional leg pain were associated with MEFV gene mutations (P 
ISSN:2328-9503
2328-9503
DOI:10.1002/acn3.50937