Factors associated with delay in diagnosis of oral cancers

•Oral cancer is one of the ten most common malignancies in the world and approximately 90 % of cases are OSCC.•Despite the progress in available treatment modalities, the mortality of patients with OSCC has remained steadily high during the last 20 years.•Early diagnosis plays a crucial role in impr...

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Veröffentlicht in:Cancer treatment and research communications 2024-01, Vol.40, p.100831, Article 100831
Hauptverfasser: Swaminathan, Deepa, George, Nebu Abraham, Thomas, Shaji, Iype, Elizabeth Mathew
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Sprache:eng
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Zusammenfassung:•Oral cancer is one of the ten most common malignancies in the world and approximately 90 % of cases are OSCC.•Despite the progress in available treatment modalities, the mortality of patients with OSCC has remained steadily high during the last 20 years.•Early diagnosis plays a crucial role in improving a patient's prognosis, as early stage cancers show a survival rate of over 90 %, whereas it drops to 5–20 % stage III and IV disease.•Both patient and tumour related factors as well as the decisions made during the first contact with health care providers influence delay before specialist consultation.•Raising awareness of HNC symptoms among the general population and GPs is the way to get patients to curative treatment without long delay. Oral cancer is one of the ten most common malignancies in the world and approximately 90 % of cases are OSCC. Despite the progress in available treatment modalities, the mortality of patients with OSCC has remained steadily high during the last 20 years. Survival data is strongly influenced by the timing of diagnosis: with more than 50 % of patients being diagnosed at an advanced stage, and their 5-year survival rate being less than 50 %. Therefore, early diagnosis plays a crucial role in improving a patient's prognosis, as early stage cancers show a survival rate of over 90 %, whereas it drops to 5–20 % stage III and IV disease. This prospective study has been conducted with an aim of assessing diagnostic delays and looking at the various patient and tumour factors and their association with them. This prospective observational study was conducted from December 2023 to February 2024. The cases for the present study included cases of oral squamous cell carcinoma diagnosed by clinical, radiological and/or histological confirmation. The patient delay was recorded in days as informed by the patients themselves, about the onset of their symptoms to time taken to seek medical attention. This was then associated with various patient and tumour related factors. A total of 120 (n) patients were interviewed and these patient's case sheets were recruited for the present study. The median primary delay for the entire population was found to be 90 days while the median secondary delay was 11 days. The median total delay was found to be 106 days. The median total delay was higher among females and younger population though this was not statistically significant. However education showed a significant impact with literate patients pre
ISSN:2468-2942
2468-2942
DOI:10.1016/j.ctarc.2024.100831