Potential link between high FIB-4 score and chronic kidney disease in metabolically healthy men

Potential link between high FIB-4 score and chronic kidney disease in metabolically healthy men

Although the association between non-alcoholic fatty liver disease and chronic kidney disease (CKD) has been well known, it is unclear whether Fibrosis-4 (FIB-4) score is a predictor of CKD development. We performed this retrospective cohort study, with a longitudinal analysis of 5-year follow-up da...

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Veröffentlicht in:Scientific reports 2022-10, Vol.12 (1), p.1-8, Article 16638
Hauptverfasser: Kuma, Akihiro, Mafune, Kosuke, Uchino, Bungo, Ochiai, Yoko, Miyamoto, Tetsu, Kato, Akihiko
Format: Artikel
Sprache:eng
Schlagworte:
692/4022
692/700/3160
Epidermal growth factor receptors
Fatty liver
Fibrosis
Glomerular filtration rate
Humanities and Social Sciences
Kidney diseases
Kidneys
Liver diseases
multidisciplinary
Proteinuria
Regression analysis
Risk factors
Science
Science (multidisciplinary)
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Zusammenfassung:Although the association between non-alcoholic fatty liver disease and chronic kidney disease (CKD) has been well known, it is unclear whether Fibrosis-4 (FIB-4) score is a predictor of CKD development. We performed this retrospective cohort study, with a longitudinal analysis of 5-year follow-up data from Japanese annual health check-ups. Participants with CKD (estimated glomerular filtration rate [eGFR] 
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-022-21039-0