Acute physical and psychological stress effects on visceral hypersensitivity in male rat: role of central nucleus of the amygdala

The aim of this study was to investigate the effects of acute physical and psychological stress and temporary central nucleus of the amygdala (CeA) block on stress-induced visceral hypersensitivity. Forty two male Wistar rats were used in this study. Animals were divided into 7 groups (n=6); 1 – Con...

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Veröffentlicht in:	Journal of Coloproctology 2017-06, Vol.37 (2), p.88-94
Hauptverfasser:	Afzali, Hamideh, Nabavizadeh, Fatemeh, Karimian, Seyed Morteza, Sohanaki, Hamid, Vahedian, Jalal, Mohamadi, Seyed Mehdi
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdominal withdrawal reflex Amygdala Amídala Estresse físico Estresse psicológico GASTROENTEROLOGY & HEPATOLOGY Hipersensibilidade visceral Original Article Physical stress Psychological stress Reflexo de retirada abdominal SURGERY Visceral hypersensitivity
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Beschreibung
Zusammenfassung:	The aim of this study was to investigate the effects of acute physical and psychological stress and temporary central nucleus of the amygdala (CeA) block on stress-induced visceral hypersensitivity. Forty two male Wistar rats were used in this study. Animals were divided into 7 groups (n=6); 1 – Control, 2 – physical stress, 3 – psychological stress, 4 – sham, 5 – lidocaine, 6 – lidocaine+physical stress and 7 – lidocaine+psychological stress. Stress induction was done using a communication box. Abdominal withdrawal reflex (AWR) score was monitored one hour after stress exposure. AWR score significantly heightened at 20, 40 and 60mmHg in the psychological stress group compared with control (p
ISSN:	2237-9363 2317-6423 2317-6423
DOI:	10.1016/j.jcol.2016.12.006