Gas chromatography mass spectrometry analysis and larvicidal activity of leaf essential oil extract of Leucas aspera against dengue, malaria and filariasis vectors
Background Insect-transmitted diseases cause high morbidity but they also include deadly diseases that cause high mortality rates among infected individuals. Several mosquito species including Aedes aegypti , Anopheles stephensi , and Culex quinquefasciatus are vectors. Ae . aegypti , a vector of ye...
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Veröffentlicht in: | Journal of basic & applied zoology 2018-11, Vol.79 (1), p.1-7, Article 49 |
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Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
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Zusammenfassung: | Background
Insect-transmitted diseases cause high morbidity but they also include deadly diseases that cause high mortality rates among infected individuals. Several mosquito species including
Aedes aegypti
,
Anopheles stephensi
, and
Culex quinquefasciatus
are vectors.
Ae
.
aegypti
, a vector of yellow fever, dengue, and chikungunya is widely distributed in the tropical and subtropical zones.
An
.
stephensi
is the primary vector of malaria in India and other west Asian countries.
C
.
quinquefasciatus
is a vector of lymphatic filariasis and it is widely distributed tropical diseases with around 120 million people infected worldwide.
Results
In the view of an increasing interest in developing plant-derived insecticides as an alternative to chemical insecticides, this study was undertaken to assess the larvicidal potential of essential oil extracted from
Leucas aspera
leaves against three medically important species of mosquito vectors,
Ae
.
aegypti
,
An
.
stephensi
, and
C
.
quinquefasciatus
. The oil extract was found to be potent against
Ae
.
Aegypti
LC
50
and LC
90
(lethal concentration LC) value of 15.59 ppm and 46.77 ppm when compared to
An
.
stephensi
(17.10 ppm and 51.20 ppm) and
C
.
quinquefasciatus
with LC
50
and LC
90
(16.19 ppm and 47.79 ppm) respectively. Gas chromatography mass spectrometry analysis of the essential oil extract of
L
.
aspera
was done to identify the major phytocompounds.
Conclusion
The results showed that the oil extract of
L
.
aspera
and its effective constituents can be considered as potent source for the production of natural larvicides. |
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ISSN: | 2090-990X 2090-990X |
DOI: | 10.1186/s41936-018-0064-0 |