An analysis of research biopsy core variability from over 5000 prospectively collected core samples

Factors correlated with biopsy tissue adequacy and the prevalence of within-biopsy variability were evaluated. Totally, 1149 research biopsies were performed on 686 patients from which 5090 cores were assessed. Biopsy cores were reviewed for malignant percentage (estimated percentage of cells in the...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:NPJ precision oncology 2021-10, Vol.5 (1), p.94-94, Article 94
Hauptverfasser: Bhamidipati, Deepak, Verma, Anuj, Sui, Dawen, Maru, Dipen, Mathew, Grace, Lang, Wenhua, Posadas, Juan, Hein, Joshua, Kopetz, Scott, Futreal, Andrew, Wistuba, Ignacio I., Gupta, Sanjay, Lee, J. Jack, Overman, Michael J., Tam, Alda L.
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Factors correlated with biopsy tissue adequacy and the prevalence of within-biopsy variability were evaluated. Totally, 1149 research biopsies were performed on 686 patients from which 5090 cores were assessed. Biopsy cores were reviewed for malignant percentage (estimated percentage of cells in the core that were malignant) and malignant area (estimated area occupied by malignant cells). Linear mixed models and generalized linear mixed models were used for the analysis. A total of 641 (55.8%) biopsies contained a core with
ISSN:2397-768X
2397-768X
DOI:10.1038/s41698-021-00234-8