Kinetics of antibody response to Coxiella burnetii infection (Q fever): Estimation of the seroresponse onset from antibody levels

Highlights • The study provides insight into the dynamics of a Coxiella burnetii infection. • Analysing antibody response kinetics enables estimation of the seroresponse onset. • The time to onset seroresponse is extremely variable among individuals. • Acute and past-resolved Q fever can be distingu...

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Veröffentlicht in:Epidemics 2015-12, Vol.13 (C), p.37-43
Hauptverfasser: Wielders, C.C.H, Teunis, P.F.M, Hermans, M.H.A, van der Hoek, W, Schneeberger, P.M
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Sprache:eng
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Zusammenfassung:Highlights • The study provides insight into the dynamics of a Coxiella burnetii infection. • Analysing antibody response kinetics enables estimation of the seroresponse onset. • The time to onset seroresponse is extremely variable among individuals. • Acute and past-resolved Q fever can be distinguished in post-epidemic/endemic areas. • The tool can estimate the Q fever outbreak/epidemic onset based on serologic data.
ISSN:1755-4365
1878-0067
DOI:10.1016/j.epidem.2015.07.001