4-(4-Amino-2-fluorophenoxy)-7-methoxyquinazolin-6-ol methanol monosolvate

In the title compound, C 15 H 12 FN 3 O 3 ·CH 3 OH, the dihedral angle between the quinazoline ring system and the benzene ring is 81.18 (9)°. In the crystal, molecules are linked by N—H...O and O—H...N hydrogen bonds, generating [10-1] chains of alternating main molecules and solvent molecules. Wea...

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Veröffentlicht in:Acta crystallographica. Section E, Structure reports online Structure reports online, 2012-04, Vol.68 (4), p.o1149-o1149
Hauptverfasser: Huang, Wei, Tan, Aimin
Format: Artikel
Sprache:eng
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Zusammenfassung:In the title compound, C 15 H 12 FN 3 O 3 ·CH 3 OH, the dihedral angle between the quinazoline ring system and the benzene ring is 81.18 (9)°. In the crystal, molecules are linked by N—H...O and O—H...N hydrogen bonds, generating [10-1] chains of alternating main molecules and solvent molecules. Weak C—H...O interactions are also observed.
ISSN:1600-5368
1600-5368
DOI:10.1107/S1600536812011725