Blood Center Testing Allows the Detection and Rapid Treatment of Acute and Recent HIV Infection

Blood donations in South Africa are tested for HIV RNA using individual donation NAT (ID-NAT), allowing detection and rapid antiretroviral therapy (ART) of acute HIV infections. We enrolled a cohort of acute and recent HIV-infected blood donation candidates in South Africa in 2015-2018, measured HIV...

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Veröffentlicht in:	Viruses 2022-10, Vol.14 (11), p.2326
Hauptverfasser:	van den Berg, Karin, Vermeulen, Marion, Bakkour, Sonia, Stone, Mars, Jacobs, Genevieve, Nyoni, Cynthia, Barker, Coreen, McClure, Christopher, Creel, Darryl, Grebe, Eduard, Roubinian, Nareg, Jentsch, Ute, Custer, Brian, Busch, Michael P, Murphy, Edward L, On Behalf Of The Recipient Epidemiology And Donor Evaluation Study Reds-Iii South Africa International Program
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antigens Antiretroviral therapy Blood Blood & organ donations Blood donors Care and treatment Consent Control Diagnosis Drug resistance Drug therapy HIV HIV (Viruses) HIV Antibodies HIV clade C HIV cure HIV infection HIV Infections - diagnosis HIV Infections - drug therapy HIV reservoir HIV-1 - genetics Human immunodeficiency virus Humans Identification and classification Infections Laboratories Plasma Ribonucleic acid RNA South Africa Viral Load
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Beschreibung
Zusammenfassung:	Blood donations in South Africa are tested for HIV RNA using individual donation NAT (ID-NAT), allowing detection and rapid antiretroviral therapy (ART) of acute HIV infections. We enrolled a cohort of acute and recent HIV-infected blood donation candidates in South Africa in 2015-2018, measured HIV antibody, ID-NAT, and recency of infection
ISSN:	1999-4915 1999-4915
DOI:	10.3390/v14112326