Study of Environmental Enteropathy and Malnutrition (SEEM) in Pakistan: protocols for biopsy based biomarker discovery and validation

Environmental Enteropathy (EE), characterized by alterations in intestinal structure, function, and immune activation, is believed to be an important contributor to childhood undernutrition and its associated morbidities, including stunting. Half of all global deaths in children

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Veröffentlicht in:	BMC pediatrics 2019-07, Vol.19 (1), p.247-17, Article 247
Hauptverfasser:	Iqbal, Najeeha T, Syed, Sana, Sadiq, Kamran, Khan, Marium N, Iqbal, Junaid, Ma, Jennie Z, Umrani, Fayaz, Ahmed, Sheraz, Maier, Elizabeth A, Denson, Lee A, Haberman, Yael, McNeal, Monica M, Setchell, Kenneth D R, Zhao, Xueheng, Qureshi, Shahida, Shen, Lanlan, Moskaluk, Christopher A, Liu, Ta-Chiang, Yilmaz, Omer, Brown, Donald E, Barratt, Michael J, Kung, Vanderlene L, Gordon, Jeffrey I, Moore, Sean R, Ali, S Asad
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Anopheles Biological markers Care and treatment Celiac disease Childhood undernutrition Children Clinical trials Diagnosis Duodenal biopsies Endoscopy Environmental enteropathy Gene expression Genes Genetic research Gut barrier function Histochemistry Intestinal diseases Low- middle income countries Malnutrition Microbiota (Symbiotic organisms) Nutrition RNA RNA sequencing Strategic planning (Business) Study Protocol Sustainable development
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Beschreibung
Zusammenfassung:	Environmental Enteropathy (EE), characterized by alterations in intestinal structure, function, and immune activation, is believed to be an important contributor to childhood undernutrition and its associated morbidities, including stunting. Half of all global deaths in children
ISSN:	1471-2431 1471-2431
DOI:	10.1186/s12887-019-1564-x