Urinary Galectin-3 as a Novel Biomarker for the Prediction of Renal Fibrosis and Kidney Disease Progression

Plasma galectin-3 (Gal-3) is associated with organ fibrosis, but whether urinary Gal-3 is a potential biomarker of kidney disease progression has never been explored. Between 2018 and 2021, we prospectively enrolled 280 patients who underwent renal biopsy and were divided into three groups based on...

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Veröffentlicht in:	Biomedicines 2022-03, Vol.10 (3), p.585
Hauptverfasser:	Ou, Shuo-Ming, Tsai, Ming-Tsun, Chen, Huan-Yuan, Li, Fu-An, Lee, Kuo-Hua, Tseng, Wei-Cheng, Chang, Fu-Pang, Lin, Yao-Ping, Yang, Ruey-Bing, Tarng, Der-Cherng
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers Biopsy Cardiovascular disease Creatinine Diabetes End-stage renal disease Epidemiology Fibrosis Galectin-3 Gene expression Genes Glomerular filtration rate Hypertension kidney disease progression Kidney diseases Microscopy Plasma Proteinuria Regression analysis renal biopsy renal fibrosis Renal function Software Transforming growth factor-b1 urinary biomarkers Urine
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Beschreibung
Zusammenfassung:	Plasma galectin-3 (Gal-3) is associated with organ fibrosis, but whether urinary Gal-3 is a potential biomarker of kidney disease progression has never been explored. Between 2018 and 2021, we prospectively enrolled 280 patients who underwent renal biopsy and were divided into three groups based on their urinary Gal-3 levels (
ISSN:	2227-9059 2227-9059
DOI:	10.3390/biomedicines10030585