Detection and circulation of hepatitis B virus immune escape mutants among asymptomatic community dwellers in Ibadan, southwestern Nigeria

Highlights • We confirmed the presence of HBV IEM in Ibadan, Southwest Nigeria. • We show for the first time that HBV IEMs are circulating in the region. • We also confirm the inclusion of Nigeria in the genotype E crescent. • Need for multiple HBV classification algorithms for isolates typing was c...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	International journal of infectious diseases 2015-10, Vol.39 (C), p.102-109
Hauptverfasser:	Faleye, Temitope Oluwasegun Cephas, Adewumi, Olubusuyi Moses, Ifeorah, Ijeoma Maryjoy, Akere, Adegboyega, Bakarey, Adeleye Solomon, Omoruyi, Ewean Chukwuma, Oketunde, Kemi, Awonusi, Oluwajumoke Bosede, Ajayi, Modupe Racheal, Adeniji, Johnson Adekunle
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Child Child, Preschool Female Genotype HBV Hepatitis B Surface Antigens - blood Hepatitis B virus Hepatitis B virus - classification Hepatitis B virus - genetics Humans Ibadan IEM Immune escape mutant Infant Infectious Disease Male Middle Aged Mutation Nigeria Phylogeny Pulmonary/Respiratory Young Adult
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Highlights • We confirmed the presence of HBV IEM in Ibadan, Southwest Nigeria. • We show for the first time that HBV IEMs are circulating in the region. • We also confirm the inclusion of Nigeria in the genotype E crescent. • Need for multiple HBV classification algorithms for isolates typing was confirmed. • HBV DNA detection alone is not sufficient for diagnosis.
ISSN:	1201-9712 1878-3511
DOI:	10.1016/j.ijid.2015.08.008