Evaluation of Ocular Perfusion Pressure in Migraine Patients: A Case-control Study

Introduction: Vascular dysregulation is a common underlying factor between migraine and glaucoma. Fluctuations in Ocular Perfusion Pressure (OPP) can lead to ischaemia and damage to the optic nerve head. It is unclear if the risk of glaucoma in migraine patients is due to low OPP. Aim: To compare the OPP of migraine patients with healthy controls and assess the role of OPP as a risk factor for glaucoma in migraine patients. Materials and Methods: This case-control study was conducted from June 2019 to May 2020 at Yenepoya Medical College Hospital, Mangaluru, Karnataka, India. Adult patients of either gender, aged between 18 and 40 years, diagnosed with migraine, were included in the study. Intraocular Pressure (IOP), blood pressure, and OPP were measured in 94 migraine patients and compared with 94 age-matched controls. Data were analysed using Statistical Package for the Social Sciences (SPSS) version 23.0. Independent t-tests were used for comparison. Adjusted odds ratios were calculated using binary logistic regression, and a p-value