Leptospirosis in Sub-Saharan Africa: a systematic review

Highlights • Leptospirosis constitutes a neglected tropical disease in sub-Saharan Africa • Climate change, increasing flooding risk, population growth, and urbanisation could increase the disease burden in the region • Leptospirosis moves into the light as an important differential diagnosis in non...

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Veröffentlicht in:	International journal of infectious diseases 2014-11, Vol.28 (C), p.47-64
Hauptverfasser:	de Vries, Sophia G, Visser, Benjamin J, Nagel, Ingeborg M, Goris, Marga G.A, Hartskeerl, Rudy A, Grobusch, Martin P
Format:	Artikel
Sprache:	eng
Schlagworte:	Africa South of the Sahara - epidemiology Animals Epidemiology Humans Incidence Infectious Disease Leptospira interrogans Leptospirosis Leptospirosis - diagnosis Leptospirosis - epidemiology Prevalence Pulmonary/Respiratory Sub-Saharan Africa Weil's disease Zoonoses - epidemiology
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Beschreibung
Zusammenfassung:	Highlights • Leptospirosis constitutes a neglected tropical disease in sub-Saharan Africa • Climate change, increasing flooding risk, population growth, and urbanisation could increase the disease burden in the region • Leptospirosis moves into the light as an important differential diagnosis in non-malarial febrile disease • Most research has been conducted in animals, probably because of the larger economic losses caused in livestock (e.g. abortion) • Future leptospirosis research should be a multi disciplinary effort, to attain the optimal health for individuals and animals
ISSN:	1201-9712 1878-3511
DOI:	10.1016/j.ijid.2014.06.013