OP-4 IMPLEMENTATION OF A RE-LINKAGE TO CARE STRATEGY IN PATIENTS WITH CHRONIC HEPATITIS C WHO WERE LOST TO FOLLOW-UP IN LATIN AMERICA

To achieve WHO's goal of eliminating HCV, innovative strategies must be designed to diagnose and treat more patients. This study aimed to describe an implementation strategy to identify patients with HCV who were lost to follow-up (LTFU) and offer them re-linkage to Figure 1. Analysis of global...

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Veröffentlicht in:Annals of hepatology 2023-03, Vol.28, p.101053, Article 101053
Hauptverfasser: Mendizabal, Manuel, Thompson, Marcos, Gonzalez-Ballerga, Esteban, Anders, Margarita, Castro-Narro, Graciela E, Pessoa, Mario G, Cheinquer, Hugo, Mezzano, Gabriel, Palazzo, Ana, Ridruejo, Ezequiel, Descalzi, Valeria, Velasco, Jose A Velarde-Ruiz, Marciano, Sebastian, Muñoz, Linda, Schinoni, Maria I, Poniachik, Jaime, Perazzo, Rosalía, Cerda, Eira, Fuster, Francisco, Varon, Adriana, García, Sandro Ruiz, Soza, Alejandro, Cabrera, Cecilia, Gomez-Aldana, Andres J, Beltrán, Flor de María, Gerona, Solange, Cocozzella, Daniel, Bessone, Fernando, Hernández, Nelia, Alonso, Cristina, Ferreiro, Melina, Antinucci, Florencia, Torre, Aldo, Moutinho, Bruna D, Borges, Silvia Coelho, Gomez, Fernando, Murga, Maria Dolores, Piñero, Federico, Sotera, Gisela F, Ocampo, Jhonier A, Mollinedo, Valeria A Cortés, Girala, Marcos, Montes, Pedro, Ratusnu, Natalia, Zuñagua, Claudia A, Castillo, Lida, Barradas, Mauricio Castillo, Chávez, Rocío, Ivantes, Cláudia, Brutti, Julia, Tenorio, Laura, Garavito, Jorge, Zevallos, Katherine, Contreras, Fernando, Infante, Mirtha, Vera-Pozo, Emilia, Tagle, Martín, Toro, Luis G, Rocha, Carlos A De La, Simian, Daniela, Silva, Marcelo O
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Sprache:eng
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Zusammenfassung:To achieve WHO's goal of eliminating HCV, innovative strategies must be designed to diagnose and treat more patients. This study aimed to describe an implementation strategy to identify patients with HCV who were lost to follow-up (LTFU) and offer them re-linkage to Figure 1. Analysis of global DNA methylation. A) Representative dot blot using anti-5mC which recognizes global methylated DNA, anti-IgG as negative control and methylene blue staining as total DNA loading control. B) Graphs shows mean ± standard deviation of 5mC densitometry brand intensity of study groups. C) Graph that represents the percentage of global methylation of the DNA analyzed with ELISA.A one-way ANOVA statistical test and a Tukey post hoc test were performed. Group NT: only received vehicle; Group HCC: damage group induced by weekly administration of DEN and 2-AAF for 12 weeks; and Group HCC/PFD: which received the same treatment as Group HCC, plus PFD (300 mg/kg) (**p
ISSN:1665-2681
2659-5982
DOI:10.1016/j.aohep.2023.101053