Effect of Intensive Blood Pressure Lowering on the Risk of Incident Silent Myocardial Infarction: A Post Hoc Analysis of a Randomized Controlled Trial

Effect of Intensive Blood Pressure Lowering on the Risk of Incident Silent Myocardial Infarction: A Post Hoc Analysis of a Randomized Controlled Trial

ABSTRACT Background Silent myocardial infarction (SMI) frequently goes undetected, yet it is associated with increased cardiovascular morbidity and mortality. The impact of intensive systolic blood pressure (SBP) lowering on the risk of SMI in those with hypertension remains uncertain. Methods In th...

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Veröffentlicht in:Annals of noninvasive electrocardiology 2024-11, Vol.29 (6), p.e70018-n/a
Hauptverfasser: Kazibwe, Richard, Ahmad, Muhammad Imtiaz, Singh, Sanjay, Chen, Lin Y., Soliman, Elsayed Z.
Format: Artikel
Sprache:eng
Schlagworte:
Age
Aged
Antihypertensive Agents - therapeutic use
Blood pressure
Blood Pressure - drug effects
Blood Pressure - physiology
blood pressure control
Cardiovascular diseases
EKG
Electrocardiography
Electrocardiography - methods
Female
Follow-Up Studies
Heart attacks
Humans
Hypertension
Hypertension - complications
Hypertension - drug therapy
Impact analysis
Incidence
Kidney diseases
Male
Middle Aged
Morbidity
Myocardial infarction
Myocardial Infarction - complications
Myocardial Infarction - prevention & control
Original
Pressure effects
Prevention
Review boards
Risk Factors
silent myocardial infarction
SPRINT
Uncertainty analysis
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Zusammenfassung:ABSTRACT Background Silent myocardial infarction (SMI) frequently goes undetected, yet it is associated with increased cardiovascular morbidity and mortality. The impact of intensive systolic blood pressure (SBP) lowering on the risk of SMI in those with hypertension remains uncertain. Methods In this post hoc analysis of the Systolic Blood Pressure Intervention Trial (SPRINT), participants with serial electrocardiograms (ECGs) during the trial were included. SPRINT investigated the benefit of intensive SBP lowering, aiming for
ISSN:1082-720X
1542-474X
1542-474X
DOI:10.1111/anec.70018