Association of sarcopenia with mortality and end‐stage renal disease in those with chronic kidney disease: a UK Biobank study

Background Sarcopenia, a degenerative and generalized skeletal muscle disorder involving the loss of muscle function and mass, is an under‐recognized problem in clinical practice, particularly in chronic kidney disease (CKD). We aimed to investigate the prevalence of sarcopenia in individuals with C...

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Veröffentlicht in:Journal of cachexia, sarcopenia and muscle sarcopenia and muscle, 2021-06, Vol.12 (3), p.586-598
Hauptverfasser: Wilkinson, Thomas J., Miksza, Joanne, Yates, Thomas, Lightfoot, Courtney J., Baker, Luke A., Watson, Emma L., Zaccardi, Francesco, Smith, Alice C.
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Sprache:eng
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Zusammenfassung:Background Sarcopenia, a degenerative and generalized skeletal muscle disorder involving the loss of muscle function and mass, is an under‐recognized problem in clinical practice, particularly in chronic kidney disease (CKD). We aimed to investigate the prevalence of sarcopenia in individuals with CKD, its risk factors, and its association with all‐cause mortality and progression to end‐stage renal disease (ESRD). Methods UK Biobank participants were grouped according to the presence of CKD (defined as an estimated glomerular filtration rate
ISSN:2190-5991
2190-6009
DOI:10.1002/jcsm.12705