O renascimento de um fármaco: talidomida The rebirth of a drug: thalidomide

O renascimento de um fármaco: talidomida The rebirth of a drug: thalidomide

Thalidomide, first synthesized in 1953, was widely prescribed for morning sickness of pregnant women from 1957 to 1961, when it was found to be seriously teratogenic, having caused serious birth defect. Nowadays, a quarter of a century later, it appears that it may be a miracle drug for such disease...

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Veröffentlicht in:Química nova 2001-10, Vol.24 (5), p.683-688
Hauptverfasser: Lídia Moreira Lima, Carlos Alberto Manssour Fraga, Eliezer J. Barreiro
Format: Artikel
Sprache:eng
Schlagworte:
leprosy
rebirth of an old drug
thalidomide
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Zusammenfassung:Thalidomide, first synthesized in 1953, was widely prescribed for morning sickness of pregnant women from 1957 to 1961, when it was found to be seriously teratogenic, having caused serious birth defect. Nowadays, a quarter of a century later, it appears that it may be a miracle drug for such diseases as leprosy, AIDS, cancer and tuberculosis.
ISSN:0100-4042
1678-7064
DOI:10.1590/S0100-40422001000500016