Genotypic and Phenotypic Expression of Antibiotic Resistance Patterns of Uropathogenic Enterobacteriaceae

Aim: To determine the antibiotic resistance patterns, detection of carbapenemase genes in uropathogenic bacilli belonging to the Enterobacteriaceae family and to correlate it with clinical data. Materials and Methods: Identification and antibiotic sensitivity testing of the uropathogenic Enterobacte...

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Veröffentlicht in:Infection and drug resistance 2022-01, Vol.15, p.3991-3999
Hauptverfasser: Gantasala, Elizabeth, Bhat, Sevitha, Saralaya, Vishwas, Jayaram, Madhumitha, Udayalaxmi, Jeppu
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Sprache:eng
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Zusammenfassung:Aim: To determine the antibiotic resistance patterns, detection of carbapenemase genes in uropathogenic bacilli belonging to the Enterobacteriaceae family and to correlate it with clinical data. Materials and Methods: Identification and antibiotic sensitivity testing of the uropathogenic Enterobacteriaceae was done by using VITEK Compact (C) system. Multiplex PCR was used to detect blaIMP, blaKPC, blaNDMl, blaOXA -48, and blaVIM genes. Results: Out of 1602 urine samples, 417 (26%) showed significant growth, and in these 311 (74.6%) belonged to the Enterobacteriaceae family. Escherichia coli showed a relatively low rate of resistance to nitrofurantoin (17/205; 8.3%), with the majority of the isolates showing a MIC value of
ISSN:1178-6973
1178-6973
DOI:10.2147/IDR.S362445