Comparison of the inflammatory response to periodontal treatment in pre and postmenopausal women

Context: Menopause is an overall increase in body's response to inflammation. Periodontium is no such exception leads to periodontitis, tooth loss may occur if not treated timely. Pre and postmenopausal conditions are more or less critical for inflammatory changes. This study aimed to determine both conditions which one was oppressive? and which reciprocated more to scaling? Materials and Methods: This is a cross-sectional interventional study. Sixty female subjects aged between 40 and 50 years with periodontitis were recruited. Equated into two groups of 30 patients each, Group I being premenopausal and Group II postmenopausal women. Plaque Index, Periodontal Index (PDI), and Sulcular Bleeding Index were compared at baseline and 3 months after scaling. IBM SPSS version 21 software was used. An independent sample t-test was applied for percentage decrement and intergroup comparison with paired t-test. Results: Significant reduction in all the above parameters in both the groups was noted based on intragroup comparison from baseline to 3 months (P < 0.001). However, the intergroup showed no significance except PDI at baseline. Conclusions: There was a remarkable effect of scaling on inflammatory conditions such as menopause and periodontitis. If women undergo periodontal therapy in premenopause stage, it can prevent future aggressive inflammatory changes in the postmenopausal stage.