Aplicación de la tractografía en la resección de tumores gliales

Purpose. To evaluate diffusion tensor imaging tractography in surgery of cerebral gliomas with res - pect to both extent of resection and follow-up outco- me, between patients that went under tractography and those who went without it. To assess the evidence of Tractography applied to surgery of cerebral gliomas and to address a grade of recommendation to it. Methods. A retrospective case-control study of 29 patients with cerebral gliomas operated on at the Department of Neurosurgery, Hospital Universita- rio Miguel Servet was performed. Sex, age, Karnofsky Performance Scale pre- and post-intervention, tumo- ral volume, extent of resection, 3-months progression and histological diagnoses were studied. Results. There was no significant difference of extent of resection neither 3-months progression bet- ween tractography group and conventional neurona - vigation group There was a trend in the study group to have an improvement in Karnofsky Performance Sca - le postintervention (Karnofsky: 90, RIC=30) compared to control group (70, RIC=70) but no significant diffe - rence was achieved. There was a positive association between the use of tractography and a higher presur- gical tumour volume. Conclusion. We could not demonstrate an as - sociation between the use of tractography and an improvement in the extent of resection or Karnofs - ky Performance Scale. We found a significant diffe - rence in presurgical tumoral volume in the study group, without a variation in the extent of resection or 3-months progression. Tractography contributes to presurgical planning and resection of cerebral glio - mas and it should be used in departments of Neuro - surgery. Objetivos. Describir las diferencias en pro - nóstico funcional, grado de resección y progresión tumoral en pacientes intervenidos de tumores glia- les con ayuda de la tractografía y pacientes interve- nidos sin ella. Establecer las indicaciones y el grado de recomendación de la tractografía en el momento actual. Material y Métodos . Estudio retrospectivo de 29 pacientes diagnosticados de lesión glial supra - tentorial en el Servicio de Neurocirugía del Hospital Universitario Miguel Servet. Las variables analiza - das han sido: sexo, edad, estado funcional según escala de Karnofsky al ingreso y en la primera revi- sión, volumen tumoral prequirúrgico, porcentaje de resección, progresión a los tres meses y estadifica - ción anatomopatológica. Resultados. No se han observado diferencias estadísticamente significati