Perfil clínico de pacientes con síndrome de Guillain Barre en un hospital universitario en Colombia

Introduction: Guillain-Barré Syndrome (GBS) is defined as progressive polyradiculoneuropathy characterized by the presence of flaccid paralysiswith symmetrical limb weakness associated with hyporeflexia or arreflexia. It is estimated that an incidence varies between 0.20-3.23 cases per 100,000 inhabitants around the world. Methods and design: A retrospective cross-sectional descriptive study. The study population was conformed by all the patients that entered a University Hospital of Colombia between 2012-2016. Patients younger than 13 years or who had an incomplete medical history were excluded. Results: A total of 55 patients were analyzed. The median age was 45 years and the median time toevolution was 5 days. Sixty percent of the patients were men. The presence of motor involvement, the initial distal involvement and the presence of decreased reflexes were present in more than 90% of the cases. There were no deaths in the hospital setting. Conclusion: The clinical characteristics found are similar to those described in the world literature. Despite the risk of ventilatory failure of these patients and the need for admission to an intensive care unit, no fatal cases were reported. The clinical presentation in this group of patients is typical, fulfilling Brighton diagnostic criteria in most cases with certainty level 1. Most patients are managed with immunoglobulin with good clinical response. Introducción: El síndrome de Guillain-Barré (SGB) se define como una polirradiculoneuropatía progresiva caracterizada por la presencia de parálisis flácida con debilidad simétrica de extremidades asociado a hiporreflexia o arreflexia. Se estima una incidencia que varía entre 0,20-3,23 casos por 100.000 habitantes alrededor del mundo. Métodos y diseño: Estudio descriptivo de corte transversal retrospectivo. La población de estudio estaba conformada por todos los pacientes que ingresaron a un Hospital Universitario de Colombia entre el período comprendido entre los años 2012-2016. Se excluyeron a los pacientes menores de 13 años o que tuvieran historia clínica incompleta. Resultados: Un total de 55 pacientes fueron analizados. La mediana de edad fue de 45 años y la Powered by Editorial Manager® and ProduXion Manager® from Aries Systems Corporation mediana de tiempo de evolución fue de 5 días. El 60% de los pacientes fueron hombres. La presencia de compromiso motor, el compromiso inicial distal y la presencia de disminución de reflejos estuvieron presentes en más del