DNA methylation-based predictors of metabolic traits in Scottish and Singaporean cohorts

DNA methylation-based predictors of metabolic traits in Scottish and Singaporean cohorts

This dataset corresponds to the study: "DNA methylation-based predictors of metabolic traits in Scottish and Singaporean cohorts". Files within this dataset include summary statistics from epigenome-wide association studies (EWASs) of six metabolic traits in Generation Scotland using two d...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Smith, Hannah M, Ng, Hong Kiat, Moodie, Joanna E, Gadd, Danni A, McCartney, Daniel L, Bernabeu, Elena, Campbell, Archie, Redmond, Paul, Taylor, Adele, Page, Danielle, Corley, Janie, Harris, Sarah E, Tay, Darwin, Deary, Ian J, Evans, Kathryn L, Robinson, Matthew R, Chambers, John C, Loh, Marie, Cox, Simon R, Marioni, Riccardo E, Hillary, Robert F
Format: Dataset
Sprache:eng
Schlagworte:
Biological Sciences::Population Biology
DNA methylation
Epigenetic scores
Epigenetics
EWAS
Metabolic traits
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Beschreibung
Zusammenfassung:This dataset corresponds to the study: "DNA methylation-based predictors of metabolic traits in Scottish and Singaporean cohorts". Files within this dataset include summary statistics from epigenome-wide association studies (EWASs) of six metabolic traits in Generation Scotland using two distinct methods OSCA and BayesR+. For the OSCA files, DNAm principal component (PC) adjusted and non-PC-adjusted results are included. Weights for six metabolic epigenetic scores (EpiScores) are included. These weights were generated using two methods: Elnet and BayesR+. EpiScore weights for each trait (and each method) are included (two files per trait).
DOI:10.7488/ds/7817