MOESM6 of SCP2-mediated cholesterol membrane trafficking promotes the growth of pituitary adenomas via Hedgehog signaling activation

Additional file 6: Figure S6. SCP2 could indirectly activate the Hh signaling through AKT/mTOR pathway. A. Protein expression levels of p-AKT, AKT, p-mTOR, mTOR and GLI1 in the different groups (SCP2-OE, Vector) were assessed by Western blotting. B. GH3 cells were treated with different concentrations of rapamycin for 48â h. Protein expression levels of p-mTOR, mTOR and GLI1 were assessed by Western blotting.